
Project III
Project III is focused on the role of immune cells in PVAT. In particular, we are interested in how immune cells in PVAT contribute to inflammation associated with high fat diet and hypertension.
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Project III is focused on the role of immune cells in PVAT. In particular, we are interested in how immune cells in PVAT contribute to inflammation associated with high fat diet and hypertension.
Specifically, we hypothesize that during health the environment of PVAT controls immune cell function and thereby prevents inflammation. Conversely, during high fat diet, we hypothesize that the environment of PVAT promotes inflammatory activity of immune cells.
Associate Professor, Dept of Pharmacology and Toxicology
Project III Collaborator, Project IV Collaborator
Associate Professor, Dept of Pharmacology & Toxicology.
Acting Director, Applied Immunology Center for Education and Research
Assistant Professor, Dept of Pharmacology & Toxicology
Project III Collaborator
Research Associate
Project III Member
Kumar, R., Jin, Y., Watts, S.W., Rockwell, C.E., “Naïve, regulatory, activated and memory immune cells coexist in PVATS that are comparable in density to non-PVAT fats in health” Front Physiol (2020) 11:58. Doi: 10.3389/fphys.2020.00058, PMID: 32116768 ...
Kumar, R., Kaiser, L.M., Rockwell, C.E., Watts, S.W., “Interleukin-10 does not contribute to the anti-contractile nature of PVAT in health”, Vasc Pharm (2021) In press ...
Kumar, R., Yang, Y., Contreras, G.A., Garver, H., Bhattacharya, S., Fink, G.D.,Rockwell, C.E.,Watts, S.W., “Phenotypic changes in T cell and macrophage subtypes in perivascular adiposetissue precede High Fat Diet-induced Hypertension”, (2021)Front. Physiol., 17 March 2021Sec.Lipid and Fatty Acid Research ...